lecture time

march 18, 2025 14:00-16:00

lecture location

conference room 426, building 4, jinfeng laboratory

lecture topic

bioeffects and sensitization strategies for pulsed electric field ablation treatment of pancreatic cancer

introduction to the speaker

zhao jun, professor at the school of basic medicine, huazhong university of science and technology, dual-recruitment professor in the department of nuclear medicine of wuhan tongji hospital, and doctoral supervisor. bachelor of science, department of chemistry, university of science and technology of china (2004), phd in biomedical engineering, purdue university, usa (2009). postdoctoral and lecturer at anderson cancer center in the united states (2009-2019). he joined huazhong university of science and technology in august 2019 and was selected for the hubei province "hundred talents plan" (2021). two national natural science foundations and one hubei province "outstanding youth" fund was approved. he serves as a member of the anticancer drug committee of the chinese anti-cancer association and a member of the oncology pharmacology committee of the chinese pharmacological society. as the first author or corresponding author, he published 14 academic papers in well-known journals such as acs nano, advanced science, nature communications, biomaterials, acta pharmacology sinica. the research field is the integration of pancreatic cancer diagnosis and treatment, including: (1) biological effects and sensitization strategies of local interventional ablation treatment; (2) drug delivery strategies for pancreatic cancer; (3) nuclear medical imaging evaluation of tumor immunotherapy prognosis. lecture abstract pancreatic cancer treatment faces challenges, and pulsed electric field ablation (pfa) technology has become a research hotspot due to its non-thermality and strong selectivity. pfa induces apoptosis of tumor cells through electroporation, activates immune responses, and inhibits angiogenesis. combined with chemotherapy, radiotherapy and immunotherapy can enhance the efficacy. in the future, precise and intelligent treatment plans and multidisciplinary collaboration will improve patient prognosis.

lecture summary

pancreatic cancer treatment faces challenges, and pulsed electric field ablation (pfa) technology has become a research hotspot due to its advantages such as non-thermality and strong selectivity. pfa induces apoptosis of tumor cells through electroporation, activates immune responses, and inhibits angiogenesis. combined with chemotherapy, radiotherapy and immunotherapy can enhance the efficacy. in the future, precise and intelligent treatment plans and multidisciplinary collaboration will improve patient prognosis.