at noon, the fengqi lake in chongqing high-tech zone is sunny and full of life. a series of unique garden-style buildings stand proudly and well-proportioned, with wide pavilions, chirping birds and fragrant flowers, surrounded by green mountains and green waters. the unique u-shaped layout and golden-red tones complement the beautiful natural landscape, reflecting modern technology. integrate and symbiosis with the natural ecology. on december 30, 2024, reporters from the sichuan-chongqing mainstream media tour event celebrating the fifth anniversary of the implementation of the chengdu-chongqing economic circle construction strategy had an intimate meeting with the jinfeng laboratory, the number one project of the western (chongqing) science city. encounter.

the reporter learned that the jinfeng laboratory, which covers an area of 128 acres and has a construction area of 135,000 square meters, is currently the largest single laboratory in the field of life and health in western my country. , an important support for jointly building a scientific and technological innovation center with national influence. its main focus is "the next generation diagnosis of major diseases." since its inauguration and commissioning in june 2022, after more than two years of exploration and practice, the laboratory has formed a "five-one" goal path and development model, namely: anchoring 1 development goal (international pathological science research center), focusing on 1 core mission (next-generation diagnosis of major diseases), implementation of 1 scientific plan (pathological phenotypic science plan), breakthrough in 1 set of key technologies (cross-scale multi-modal disease imaging technology system), and formation of 1 type of iconic results (new system of disease classification).

"the main feature of our laboratory is the innovation of institutional mechanisms. we are the first to explore the implementation of the task list system in organized scientific research - set tasks first and then recruit people, and combine them around major scientific issues and clinical needs to form a task list; in terms of project organization methods be the first to realize the integrated design of basic research, applied basic research and translational research, coordinate the design of projects, better reflect the intersection of disciplines, and finally realize the tasks that are visible and tangible. at present, our laboratory has gathered 19 leading teams in this field across the country and even the world to carry out scientific research, with a total of 477 scientific researchers. from the beginning, we have attached great importance to the complementary advantages between the two parties. , the laboratory expert committee has included sichuan experts from the beginning, and sichuan and chongqing have jointly established a key laboratory..." said xu hui, deputy director of jinfeng laboratory.

in the pathological phenotype laboratory on the third floor of jinfeng laboratory, all kinds of advanced experimental equipment are available. directors of the cancer institute and deputy director of the cancer center of sichuan provincial people's hospital and the affiliated hospital of university of electronic science and technology of china, jinfeng laboratory part-time project leader xu chuan is guiding postdoctoral fellow wang huani and graduate student li xurui to carry out protein purification research. “the construction of the chengdu-chongqing twin-city economic circle provides opportunities for scientific research cooperation between sichuan and chongqing scientific and technological workers. there is an open scientific research environment, a good scientific research atmosphere and sufficient scientific research guarantees. as long as you want to make a difference in scientific research and have a scientific research foundation, anyone who has the ability and ability can pass the assessment and come here to work on key problems together." xu chuan told reporters that the research team he leads has seven doctoral students from peking university, sichuan university, xiamen university, macau university and other universities participating full-time in the laboratory. work.

in fact, the pathology department and pathology technology have a history of nearly a hundred years in our country. chongqing attaches great importance to exchanges and cooperation with sichuan in pathology departments. sichuan and chongqing not only jointly established the western china pathology alliance, but also jointly undertook the national natural science foundation of china with the sichuan provincial people's hospital to promote collaborative scientific research between sichuan and chongqing. comprehensive research project of the ministry of science “immune checkpoint-based confirmation and preclinical research of the druggability of the originally discovered antibody molecule ncab01." in november 2023, jinfeng laboratory, tianfu jincheng laboratory, chongqing-guangdong pathological science research center and other units jointly hosted the first "belt and road" science and technology exchange conference "future medical innovation cooperation forum". in november this year, at the signing ceremony of the chongqing-chengdu dual-core linkage joint construction cooperation project, jinfeng laboratory signed a strategic cooperation agreement with sichuan tianfu jincheng laboratory (future medical city).

the sichuan-chongqing key laboratory that xu hui is talking about refers to the "sichuan-chongqing jointly construction of pathological examination and diagnosis" jointly declared by sichuan provincial people's hospital, southwest hospital, the first affiliated hospital of chongqing medical university, and jinfeng laboratory in november 2024. key laboratory". with this as a link, the two provinces and cities of sichuan and chongqing have established multi-disciplinary interdisciplinary teams to carry out research on innovative theories and diagnostic technologies. jinfeng laboratory has also joined forces with top experts in pathology, clinical, laboratory, imaging and other disciplines from sichuan and chongqing to focus on "difficult problems" " and "innovation", committed to building the world's top diagnostic platform - jinfeng pathological precision diagnosis center, carrying out three major businesses: mdt remote consultation, innovative diagnostic technology services, and diagnostic quality control services, accelerating the "next generation diagnostic technology for major diseases "transformation of results.

the reporter noticed that pathological examination and diagnosis in the sichuan-chongqing key laboratory (in preparation) are not easy! the laboratory is led by professor bian xiuwu and professor yang zhenglin, the only academicians of the chinese academy of sciences in the field of pathology and the only field of clinical testing. it has more than 300 pathological testing and diagnostic talents represented by national distinguished young scholars, yangtze river scholars, and national leading talents of ten thousand people, and is a national leader. the pathological examination and diagnosis research team has first-class clinical resources and platform advantages in the country, and the research capabilities in the field of pathological examination and diagnosis are leading in the country. aiming at the new model of disease diagnosis and treatment in the medical era, we will carry out research in four aspects: new technologies and systems for precise pathological diagnosis, new technologies for disease pathological examination and diagnosis, new pathological resources and standardized big data and their applications, new technologies for examination and diagnosis and their applications, to highlight solutions key technical problems in early detection of diseases and personalized precise diagnosis and treatment. currently, we have jointly established a cancer stem cell microenvironment platform, a pathological phenotyping platform, a spatiotemporal omics platform, a nanosynthesis platform, a clinical pathology diagnosis platform, a laboratory diagnosis technology platform, and a disease 8 high-level platforms including sample library platform and artificial intelligence platform.